Algomtl
svgfair.com
 
综合性体外致心律失常评价|药物筛选服务|离子通道服务|激酶谱筛选|膜片钳服务
Details
China Medical
Medical

综合性体外致心律失常评价|药物筛选服务|离子通道服务|激酶谱筛选|膜片钳服务

  • 心脏复极毒性（QT间期延长及尖端扭转型室性心动过速）是严重而广泛的不良反应，撤市的药物中1/3由于药物致心律失常不良反应导致。

  • 抑制hERG钾通道，是致心律失常毒性的主要原因。2005年颁布的ICHS7B要求所有申报阶段的供试品必须有对hERG抑制率的数据，cF DA（NMPA）的“药物QT间期延长潜在作用非临床研究技术指导原则”（2014）也有相应规定。 、

  • hERG作为评价药物致心律失常毒性的主要指标，敏感性和特异性都存在比较严重的问题，因此，2013年FDA开始推动综合性体外致心律失常评 价（CiPA, Comprehensive in vitro Proarrhythmia Assay）。

  • CiPA包括四个核心环节：（1）心脏多种离子通道评价（2）动作电位的计算机虚拟重建（3）iPSC诱导分化心肌细胞模型（4）临床心电图评 估。

  • ICH关于CiPA的时间计划表：2020年6月，将以ICHS7B Q&A的更新形式推出。

23.png

爱思益普体外心脏安全性评价服务

1，心脏多离子通道作用研究

24.jpg

1586341151905197.png

2，干细胞诱导分化心肌细胞动作电位

26.jpg

3，浦肯野纤维动作电位

27.jpg

Location : 北京市通州区科创十三街与经海路交汇处, 100176 beijing,
Contact : Huanyu Shang, +17 3 56 52 16 13

Good deal: buying from seller

Visit our guide for a secure transaction! Under no circumstances Algomtl can be held responsible for the content of the ads published. Only the sellers and buyers responsability is involved in case of dispute.
We invite you to read our terms of use. You can also visit our FAQ section and see our information section on the risks associated with counterfeiting.
This page is about importers and exporters of
综合性体外致心律失常评价|药物筛选服务|离子通道服务|激酶谱筛选|膜片钳服务

Search in a category : Medical
Search in a category :
综合性体外致心律失常评价|药物筛选服务|离子通道服务|激酶谱筛选|膜片钳服务
Thailand 5000 Food
100% pure Perilla Seed

Saturday, February 20, 2016

Quantity : 1000 MT PE - Price : 400 usd per mt CIF

We supply top quality Dill Seeds at desirable quantities and at very good prices. The Dill Seeds are certify organic and are ready for shipment to any destination in the world. air dried perilla seed Name air dried perilla seed Item No. PD-TW-144 Grade AAA Features No speckle...

Khun Jack Partnership Ltd

  • 5000 - Chaing Mai
  • +66 9 68 75 20 43
France 015400 Food
2014 GSW pumpkin kernel pumpkin seeds Grade AA,A, AAA

Tuesday, May 26, 2026

San Xin Trade Co., Ltd. is a factory engaged in producing and export sunflower kernels,shine skin pumpkin seeds kernels,pumpkin seeds grown without shell. aimme@sanxinfood.com The company located in HeTao plain,Inner Mongolia,here is the original place of sunflower and pumpkin which...

San Xin Trade Co.,Ltd

  • Aimme
  • 015400 - Shanba
  • +86 478 6620015
France 57500 Clothes
Destockage lot Jeans Diesel homme

Saturday, November 08, 2014

Quantity : 5 - Price : 40,00 €

Retrouver cet article sur : WWW.TEXMARK.FR - Destockeur/Fournisseur de la marque DIESEL en lot. - - Tarifs sur simple inscription sur Texmark.fr, site de vente en ligne. - - Détails pour Lot Jeans Diesel HOMME "WAYKEE 2014" - - REGULAR STRAIGHT - Lot de 5 pièces Longueur 32 ...

SARL TEXMARK

 
Secure payment

Information

Top search