Overview of SPE Technique

SPE Technique Introduction

SPE(Solid-phase Extraction), is an increasingly popularized technology of sample pretreatment, which is established on the basis of traditional LLE(Liquid-liquid Extraction). Combined with the substance interaction mechanism that like dissolves like, and basic knowledge of stationary phases with currently widely applied HPLC(High-Performance Liquid Chromatography) and GC(Gas Chromatography), the skill has been gradually developed.
Besides, SPE features a small number of organic solvents, convenience, safety, and high efficiency.

SPE Technique Category

According to the similar dissolution mechanism, SPE can be divided into four types– reverse SPE, positive SPE, ion exchange SPE, and adsorption SPE.

SPE Technique General Applications

SPEs are mostly utilized to treat liquid samples extracting, concentrating and purifying the semi-volatile and non-volatile compounds. If solid samples are provided, they have to be processed into liquids ahead. Nowadays, domestic applications mainly focus on the analysis of polycyclic aromatic hydrocarbons(PAHs) and polychlorinated biphenyls(PCBs) for watery conditions, pesticide and herbicide residues in fruits, vegetables and food, antibiotic analysis and clinical drug analysis.

SPE Technique Typical Applications

● Biological fluid analysis
● Analysis and monitoring of drinking water, groundwater, and sewage
● Volatile oils, plant tissues, fruits, vegetables, and grains
● Liquid drug samples, soils, and sediments
● Meat, fish and other animal tissues
● Tablets and other solid drugs